Jump to main content
Jump to site search

Issue 39, 2015
Previous Article Next Article

Self-assembly of bi-functional peptides on large-pore mesoporous silica nanoparticles for miRNA binding and delivery

Author affiliations

Abstract

Bi-functional peptides were designed to have binding abilities for both silica nanoparticles and miRNAs. Non-covalent self-assembly of peptides on large pore mesoporous silica nanoparticles provides a delivery system that shows a high binding capacity for nucleic acids, strong transfection efficiency of miRNA and attractive down-regulation of protein expression.

Graphical abstract: Self-assembly of bi-functional peptides on large-pore mesoporous silica nanoparticles for miRNA binding and delivery

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 Jun 2015, accepted on 09 Sep 2015 and first published on 11 Sep 2015


Article type: Communication
DOI: 10.1039/C5TB01133G
J. Mater. Chem. B, 2015,3, 7653-7657

  •   Request permissions

    Self-assembly of bi-functional peptides on large-pore mesoporous silica nanoparticles for miRNA binding and delivery

    J. Lu, H. Shen, Z. Wu, B. Wang, D. Zhao and L. He, J. Mater. Chem. B, 2015, 3, 7653
    DOI: 10.1039/C5TB01133G

Search articles by author

Spotlight

Advertisements