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Issue 28, 2015
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Tailoring a two-dimensional graphene oxide surface: dual T1 and T2 MRI contrast agent materials

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Abstract

A generalized strategy for developing a hybrid two-dimensional nanostructured dual T1T2 MRI contrast agent (CA), by co-loading graphene oxide with both Mn-doped Fe3O4 (T2 agent) and MnO (T1 agent) magnetic nanoparticles, is reported. Typical T1/T2 signal quenching, due to magnetic coupling, was not observed because of the fair T1 CA separation distance from the T2 CA on the graphene oxide. The resultant two-dimensional nanostructured MRI CA complements the existing dual T1T2 MRI CA libraries.

Graphical abstract: Tailoring a two-dimensional graphene oxide surface: dual T1 and T2 MRI contrast agent materials

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Supplementary files

Article information


Submitted
13 May 2015
Accepted
17 Jun 2015
First published
17 Jun 2015

J. Mater. Chem. B, 2015,3, 5678-5682
Article type
Communication
Author version available

Tailoring a two-dimensional graphene oxide surface: dual T1 and T2 MRI contrast agent materials

E. Peng, F. Wang, S. Tan, B. Zheng, S. F. Y. Li and J. M. Xue, J. Mater. Chem. B, 2015, 3, 5678
DOI: 10.1039/C5TB00902B

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