Cu2+-embedded carbon nanoparticles as anticancer agents

Abstract

We report the synthesis of luminescent carbon nanoparticles (93 ± 50 nm) embedded with Cu²⁺. It was observed that at a relatively low concentration of Cu²⁺ (2.55 ppm), cervical cancer HeLa cells died due to apoptosis induced by the nanoparticles. Also, generation of reactive oxygen species in the cells, in the presence of the composite nanoparticles, has been attributed to their killing. The luminescence of the carbon nanoparticles was used for imaging of the cells.