Thermo- and photo-enhanced microtubule formation from Ru(bpy)32+-conjugated tubulin

Kosuke Okeyoshi; Ryuzo Kawamura; Ryo Yoshida; Yoshihito Osada

doi:10.1039/C3TB21242D

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Thermo- and photo-enhanced microtubule formation from Ru(bpy)₃²⁺-conjugated tubulin†

Kosuke Okeyoshi,^ab Ryuzo Kawamura,^a Ryo Yoshida^b and Yoshihito Osada*^a

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* Corresponding authors

^a RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan
E-mail: osadayoshi@riken.jp
Fax: +81 48 467 9300
Tel: +81 48 467 2816

^b Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

Abstract

Ru(bpy)₃²⁺-conjugated tubulin is able to substantially enhance polymerization to form microtubules with increased rate at lower temperatures. Additionally, the polymerization is enhanced by photo-irradiation and the possible mechanism is discussed focusing on the photo-thermal energy conversion.

This article is part of the themed collection: 2014 Journal of Materials Chemistry B Hot Articles

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Article information

DOI: https://doi.org/10.1039/C3TB21242D
Article type: Communication
Submitted: 09 Sep 2013
Accepted: 31 Oct 2013
First published: 01 Nov 2013

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J. Mater. Chem. B, 2014,2, 41-45

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Thermo- and photo-enhanced microtubule formation from Ru(bpy)₃²⁺-conjugated tubulin

K. Okeyoshi, R. Kawamura, R. Yoshida and Y. Osada, J. Mater. Chem. B, 2014, 2, 41 DOI: 10.1039/C3TB21242D

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Journal of Materials Chemistry B