Issue 45, 2013

Fe doped CdTeS magnetic quantum dots for bioimaging

Abstract

A facile synthesis of 3–6 nm, water dispersible, near-infrared (NIR) emitting, quantum dots (QDs) magnetically doped with Fe is presented. Doping of alloyed CdTeS nanocrystals with Fe was achieved in situ using a simple hydrothermal method. The magnetic quantum dots (MQDs) were capped with N-acetyl-cysteine (NAC) ligands, containing thiol and carboxylic acid functional groups to provide stable aqueous dispersion. The optical and magnetic properties of the Fe doped MQDs were characterized using several techniques. The synthesized MQDs are tuned to emit in the vis-NIR (530–738 nm) wavelength regime and have high quantum yields (67.5–10%). NIR emitting (738 nm) MQDs having 5.6 atomic% Fe content exhibited saturation magnetization of 85 emu per g [Fe] at room temperature. Proton transverse relaxivity of the Fe doped MQDs (738 nm) at 4.7 T was determined to be 3.6 mM−1 s−1. The functional evaluation of NIR MQDs has been demonstrated using phantom and in vitro studies. These water dispersible, NIR emitting and MR contrast producing Fe doped CdTeS MQDs, in an unagglomerated form, have the potential to act as multimodal contrast agents for tracking live cells.

Graphical abstract: Fe doped CdTeS magnetic quantum dots for bioimaging

Supplementary files

Article information

Article type
Paper
Submitted
17 Jun 2013
Accepted
13 Sep 2013
First published
16 Sep 2013

J. Mater. Chem. B, 2013,1, 6312-6320

Fe doped CdTeS magnetic quantum dots for bioimaging

A. K. Saha, P. Sharma, H. Sohn, S. Ghosh, R. K. Das, A. F. Hebard, H. Zeng, C. Baligand, G. A. Walter and B. M. Moudgil, J. Mater. Chem. B, 2013, 1, 6312 DOI: 10.1039/C3TB20859A

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