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Issue 37, 2013
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Aptide-conjugated liposome targeting tumor-associated fibronectin for glioma therapy

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Abstract

Aptides, developed by our laboratory, are a novel class of high-affinity peptides. Here, we describe the conjugation of an aptide targeting extra-domain B (EDB) of tumor-associated fibronectin to drug-containing liposomes and explore the potential of these aptide-conjugated liposomes as a robust and efficient targeted drug-delivery system for glioma therapy.

Graphical abstract: Aptide-conjugated liposome targeting tumor-associated fibronectin for glioma therapy

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Publication details

The article was received on 07 Jun 2013, accepted on 05 Aug 2013 and first published on 06 Aug 2013


Article type: Communication
DOI: 10.1039/C3TB20815J
J. Mater. Chem. B, 2013,1, 4723-4726

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    Aptide-conjugated liposome targeting tumor-associated fibronectin for glioma therapy

    P. E. Saw, S. Kim, I. Lee, J. Park, M. Yu, J. Lee, J. Kim and S. Jon, J. Mater. Chem. B, 2013, 1, 4723
    DOI: 10.1039/C3TB20815J

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