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Issue 34, 2013
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Dendrimer-based nanodevices for targeted drug delivery applications

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Abstract

This review reports some recent advances on the use of dendrimers as a versatile platform for targeted drug delivery applications. The unique 3-dimensional architectures and macromolecular characteristics afford dendrimers with ideal drug delivery ability through encapsulating drugs in their interior or covalently conjugating drugs on their surfaces. The adaptable surface functionalization ability enables covalent conjugation of various targeting molecules onto the surface of dendrimers, thereby allowing for generation of various multifunctional nanodevices for targeted drug delivery applications. In particular, the application of dendrimers as versatile platforms for targeted cancer therapeutics will be introduced in detail.

Graphical abstract: Dendrimer-based nanodevices for targeted drug delivery applications

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Article information


Submitted
22 May 2013
Accepted
10 Jul 2013
First published
11 Jul 2013

J. Mater. Chem. B, 2013,1, 4199-4211
Article type
Feature Article

Dendrimer-based nanodevices for targeted drug delivery applications

J. Zhu and X. Shi, J. Mater. Chem. B, 2013, 1, 4199
DOI: 10.1039/C3TB20724B

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