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Issue 17, 2013
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Crumpled reduced graphene oxide–polyamidoamine dendrimer hybrid nanoparticles for the preparation of an electrochemical biosensor

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Abstract

Reduced graphene nanoparticles were prepared from graphene oxide through a two-step covalent modification approach. Graphene oxide was first enriched with reactive epoxy groups by anchoring (3-glycidyloxypropyl)trimethoxysilane at the hydroxyl groups located on the nanocarbon basal plane. Modified graphene oxide was further cross-linked and partially reduced by treatment with the fourth-generation ethylenediamine core polyamidoamine G-4 dendrimer producing graphene nanoparticles with crumpled paper-like morphology. This graphene derivative was employed as a coating material for glassy carbon electrodes and the nanostructured electrode was tested for the preparation of electrochemical biosensors by immobilizing the enzyme tyrosinase through cross-linking with glutaraldehyde. This bioelectrode showed excellent electroanalytical behavior for catechol with a fast response in about 6 s, linear range of 10 nM to 22 μM, sensitivity of 424 mA M−1, and low detection limit of 6 nM. The enzyme biosensor also showed high stability when stored at 4 °C under dry and wet conditions.

Graphical abstract: Crumpled reduced graphene oxide–polyamidoamine dendrimer hybrid nanoparticles for the preparation of an electrochemical biosensor

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Publication details

The article was received on 20 Jan 2013, accepted on 01 Mar 2013 and first published on 01 Mar 2013


Article type: Paper
DOI: 10.1039/C3TB20078G
J. Mater. Chem. B, 2013,1, 2289-2296

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    Crumpled reduced graphene oxide–polyamidoamine dendrimer hybrid nanoparticles for the preparation of an electrochemical biosensor

    E. Araque, R. Villalonga, M. Gamella, P. Martínez-Ruiz, J. Reviejo and J. M. Pingarrón, J. Mater. Chem. B, 2013, 1, 2289
    DOI: 10.1039/C3TB20078G

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