Artificial magnetotactic probiotics for in vivo targeting therapy

Abstract

Artificial magnetotactic probiotics (AMPs) are developed to combine living probiotic benefits with magnetic targeting properties. Experimental investigations are carried out to study their surface nano-modification process, viability and magnetic motility behavior. Subsequent in vivo studies indicate that AMPs can be applied to inhibit different invasive pathogens, including some antibiotic-resistant strains. Compared with conventional antibiotic therapy, AMPs represent an efficient and accurate alternative treatment for dealing with microbial threats, and have the potential to minimize a wide range of adverse effects.