Issue 43, 2019

The influence of device handles in single-molecule experiments

Abstract

We deduce a fully analytical model to predict the artifacts of the device handles in single molecule force spectroscopy experiments. As we show, neglecting the handle stiffness can lead to crucial overestimation or underestimation of the stability properties and unfolding thresholds of multistable molecules.

Graphical abstract: The influence of device handles in single-molecule experiments

Supplementary files

Article information

Article type
Paper
Submitted
08 Jul 2019
Accepted
28 Sep 2019
First published
02 Oct 2019

Soft Matter, 2019,15, 8680-8690

The influence of device handles in single-molecule experiments

L. Bellino, G. Florio and G. Puglisi, Soft Matter, 2019, 15, 8680 DOI: 10.1039/C9SM01376H

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