Jump to main content
Jump to site search

Issue 23, 2018
Previous Article Next Article

Polymer nanoparticle sizes from dynamic light scattering and size exclusion chromatography: the case study of polysilanes

Author affiliations

Abstract

Dynamic light scattering (DLS) and size exclusion chromatography (SEC) are among the most popular methods for determining polymer sizes in solution. Taking dendritic and network polysilanes as a group of least soluble polymer substances, we critically compare and discuss the difference between nanoparticle sizes, obtained by DLS and SEC. Polymer nanoparticles are typically in poor solution conditions below the theta point and are therefore in the globular conformation. The determination of particle sizes in the presence of attractive interactions is not a trivial task. The only possibility to measure, aggregation-free, the true molecular size of polymer nanoparticles in such a solution regime, is to perform the experiment with a dilute solution of globules (below the theta point and above the miscibility line). Based on the results of our polysilane measurements, we come to a conclusion that DLS provides more reliable results than SEC for dilute solutions of globules. General implications for the size measurements of polymer nanoparticles in solution are discussed.

Graphical abstract: Polymer nanoparticle sizes from dynamic light scattering and size exclusion chromatography: the case study of polysilanes

Back to tab navigation

Publication details

The article was received on 16 Apr 2018, accepted on 15 May 2018 and first published on 16 May 2018


Article type: Paper
DOI: 10.1039/C8SM00780B
Citation: Soft Matter, 2018,14, 4735-4740
  •   Request permissions

    Polymer nanoparticle sizes from dynamic light scattering and size exclusion chromatography: the case study of polysilanes

    A. Badasyan, A. Mavrič, I. Kralj Cigić, T. Bencik and M. Valant, Soft Matter, 2018, 14, 4735
    DOI: 10.1039/C8SM00780B

Search articles by author

Spotlight

Advertisements