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Issue 44, 2013
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Self-organization of the bacterial cell-division protein FtsZ in confined environments

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Abstract

We report a microfluidic approach to generate aqueous droplets in oil of different dimensionality, stabilized by a lipid monolayer, to systematically probe the polymerization of bacterial cell-division protein FtsZ into fibrous networks as a function of the concentrations of crowding agent, FtsZ, and GTP. FtsZ bundles confined in droplets were dynamic, and their distribution depended on the intrinsic properties of the system and restrictions imposed by the spatial boundaries.

Graphical abstract: Self-organization of the bacterial cell-division protein FtsZ in confined environments

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Article information


Submitted
26 Apr 2013
Accepted
27 Jun 2013
First published
27 Jun 2013

Soft Matter, 2013,9, 10493-10500
Article type
Paper

Self-organization of the bacterial cell-division protein FtsZ in confined environments

S. Mellouli, B. Monterroso, H. R. Vutukuri, E. T. Brinke, V. Chokkalingam, G. Rivas and W. T. S. Huck, Soft Matter, 2013, 9, 10493
DOI: 10.1039/C3SM51163D

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