Issue 40, 2012

Hyaluronan and phospholipids in boundary lubrication

Abstract

Hyaluronan has been found to play an important role in boundary lubrication in joints, but model experiments have shown that free hyaluronan is reluctant to stay between surfaces. We show that hyaluronan, when assisted by a phospholipid bilayer, can act as a boundary lubricant, even at pressures well above those leading to breakdown of cartilage.

Graphical abstract: Hyaluronan and phospholipids in boundary lubrication

Supplementary files

Article information

Article type
Communication
Submitted
12 Jul 2012
Accepted
21 Aug 2012
First published
07 Sep 2012

Soft Matter, 2012,8, 10241-10244

Hyaluronan and phospholipids in boundary lubrication

C. Liu, M. Wang, J. An, E. Thormann and A. Dėdinaitė, Soft Matter, 2012, 8, 10241 DOI: 10.1039/C2SM26615F

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