Controlling bacterial adhesion to surfaces using topographical cues: a study of the interaction of Pseudomonas aeruginosa with nanofiber-textured surfaces

Abstract

The state of adhesion of bacteria to nanofiber-textured model surfaces is analyzed at a single-cell level. The results reveal similarities between the effect of topography on bacteria–surface interactions and vesicle–surface interactions. The results are discussed in the context of controlling bacterial adhesion to surfaces using nanofibrous topographical features.