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Issue 28, 2012
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Supramolecular hydrogels formed by the conjugates of nucleobases, Arg-Gly-Asp (RGD) peptides, and glucosamine

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Abstract

Here we report the generation of a novel class of supramolecular hydrogelators based on the integration of nucleobases, Arg-Gly-Asp (RGD) peptides, and glucosamine in a single molecule. These novel small molecule hydrogelators self-assemble in water to form stable supramolecular nanofibers/hydrogels and exhibit useful biostability. This approach provides a new opportunity for systematic exploration of the self-assembly of small biomolecules by varying any individual segment to generate a large array of supramolecular hydrogels for biological functions and for biomedical applications.

Graphical abstract: Supramolecular hydrogels formed by the conjugates of nucleobases, Arg-Gly-Asp (RGD) peptides, and glucosamine

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Publication details

The article was received on 28 Mar 2012, accepted on 10 May 2012 and first published on 14 Jun 2012


Article type: Paper
DOI: 10.1039/C2SM25725D
Citation: Soft Matter, 2012,8, 7402-7407

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    Supramolecular hydrogels formed by the conjugates of nucleobases, Arg-Gly-Asp (RGD) peptides, and glucosamine

    X. Li, X. Du, Y. Gao, J. Shi, Y. Kuang and B. Xu, Soft Matter, 2012, 8, 7402
    DOI: 10.1039/C2SM25725D

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