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Issue 18, 2012
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Supramolecular hydrogels based on antimycobacterial amphiphiles

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Abstract

Synthetic modification of antimycobacterial 4-alkoxy-anilines yields low molecular weight amphiphiles. The bioactivity is retained in these amphiphiles and shows alkyl chain length specificity. The self-assembly behaviour in aqueous media was investigated. It was found that several of these new compounds are capable of forming thermoreversible supramolecular hydrogels in alkaline aqueous media. The initial drug can be released from the hydrogel by thermal hydrolysis.

Graphical abstract: Supramolecular hydrogels based on antimycobacterial amphiphiles

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Publication details

The article was received on 23 Dec 2011, accepted on 15 Mar 2012 and first published on 29 Mar 2012


Article type: Communication
DOI: 10.1039/C2SM07456G
Soft Matter, 2012,8, 4873-4876

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    Supramolecular hydrogels based on antimycobacterial amphiphiles

    A. Bernet, M. Behr and H. Schmidt, Soft Matter, 2012, 8, 4873
    DOI: 10.1039/C2SM07456G

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