Issue 10, 2012
From the journal:

Soft Matter

Reversible regulation of bioactive ligands presented on immobilized gold nanoparticles†

Xintong Wang,a   Jeremiah J. Riesberga  and  Wei Shen*a  

* Corresponding authors

a Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota, United States
E-mail: shenx104@umn.edu
Fax: +1 612 626 6583
Tel: +1 612 624 3771

Abstract

A polypeptide fusion of a bioactive ligand and a coiled-coil A was functionalized on gold nanoparticles, which were subsequently immobilized on substrates. The accessibility of the ligand could be reversibly controlled via co-immobilization and removal of B-poly(ethylene) glycol through heterodimerization between A and the complementary coiled-coil B.

Graphical abstract: Reversible regulation of bioactive ligands presented on immobilized gold nanoparticles

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Article information

DOI
https://doi.org/10.1039/C2SM06567C
Article type
Communication
Submitted
16 Aug 2011
Accepted
06 Jan 2012
First published
01 Feb 2012

Soft Matter, 2012,8, 2812-2815

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Reversible regulation of bioactive ligands presented on immobilized gold nanoparticles

X. Wang, J. J. Riesberg and W. Shen, Soft Matter, 2012, 8, 2812 DOI: 10.1039/C2SM06567C

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