Issue 25, 2019
From the journal:

Chemical Science

A ruthenium(ii)-catalyzed C–H allenylation-based approach to allenoic acids†

Xiaoyan Wu, ORCID logo a   Junjie Fan,a   Chunling Fua  and  Shengming Ma ORCID logo *a  

* Corresponding authors

a Laboratory of Molecular Recognition and Synthesis, Department of Chemistry, Zhejiang University, Hangzhou 310027, Zhejiang, People's Republic of China
E-mail: masm@sioc.ac.cn

Abstract

A Ru(II)-catalyzed direct access to various functionalized allenoic acids via C–H allenylation of readily available aryl carboxylic acids with propargylic acetates is reported. Axially chiral allenoic acids could be obtained in high ee by using optically active propargylic acetates through a chirality transfer strategy.

Graphical abstract: A ruthenium(ii)-catalyzed C–H allenylation-based approach to allenoic acids

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C9SC00603F
Article type
Edge Article
Submitted
02 Feb 2019
Accepted
04 May 2019
First published
10 May 2019
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2019,10, 6316-6321

Permissions

Request permissions

A ruthenium(II)-catalyzed C–H allenylation-based approach to allenoic acids

X. Wu, J. Fan, C. Fu and S. Ma, Chem. Sci., 2019, 10, 6316 DOI: 10.1039/C9SC00603F

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements