Issue 47, 2020, Issue in Progress
From the journal:

RSC Advances

Rhizovagine A, an unusual dibenzo-α-pyrone alkaloid from the endophytic fungus Rhizopycnis vagum Nitaf22†

Ali Wang,a   Siji Zhao,a   Gan Gu,a   Dan Xu,a   Xuping Zhang,a   Daowan Lai ORCID logo *a  and  Ligang Zhou ORCID logo *a  

* Corresponding authors

a Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, China
E-mail: dwlai@cau.edu.cn, lgzhou@cau.edu.cn

Abstract

Rhizovagine A (1), a novel dibenzo-α-pyrone alkaloid with an unprecedented 5/5/6/6/6 fused pentacyclic skeleton, was isolated from the endophytic fungus Rhizopycnis vagum Nitaf22. The structure was elucidated by comprehensive spectroscopic analysis, in combination with quantum chemical 13C NMR and electronic circular dichroism (ECD) calculations for configurational assignment. A plausible biosynthetic pathway for 1 was proposed. Compound 1 displayed acetylcholinesterase inhibitory activity.

Graphical abstract: Rhizovagine A, an unusual dibenzo-α-pyrone alkaloid from the endophytic fungus Rhizopycnis vagum Nitaf22

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Article information

DOI
https://doi.org/10.1039/D0RA05022A
Article type
Paper
Submitted
07 Jun 2020
Accepted
20 Jul 2020
First published
27 Jul 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 27894-27898

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Rhizovagine A, an unusual dibenzo-α-pyrone alkaloid from the endophytic fungus Rhizopycnis vagum Nitaf22

A. Wang, S. Zhao, G. Gu, D. Xu, X. Zhang, D. Lai and L. Zhou, RSC Adv., 2020, 10, 27894 DOI: 10.1039/D0RA05022A

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