Issue 22, 2020

Projection method as a probe for multiplexing/demultiplexing of magnetically enriched biological tissues

Abstract

The unmet demand for cheap, accurate, and fast multiplexing of biomarkers has urged nanobiotechnology to prioritize the invention of new biomarkers that make feasible the remote detection, identification, and quantification of biological units, such as regenerative tissues. Here, we introduce a novel approach that highlights magnetic nanowires (MNWs) with such capabilities. This method employs the stable magnetization states of MNWs as a unique characteristic that can be realized by projecting the MNWs' switching field on the backward field (PHb), also known as the irreversible switching field. Experimentally, several types of MNWs were directly synthesized inside polycarbonate tissues and their PHb characteristics were measured and analyzed. Our results show that the PHb gives an excellent identification and quantification characteristic for demultiplexing MNWs embedded in these tissues. Furthermore, this method significantly improves the characterization speed by a factor of 50×–100× that makes it superior to the current state of the art that ceased the progression of magnetic nanoparticles in multiplexing/demultiplexing applications.

Graphical abstract: Projection method as a probe for multiplexing/demultiplexing of magnetically enriched biological tissues

Supplementary files

Article information

Article type
Paper
Submitted
18 Feb 2020
Accepted
24 Mar 2020
First published
01 Apr 2020
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2020,10, 13286-13292

Projection method as a probe for multiplexing/demultiplexing of magnetically enriched biological tissues

M. R. Zamani Kouhpanji and B. J. H. Stadler, RSC Adv., 2020, 10, 13286 DOI: 10.1039/D0RA01574A

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