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Issue 37, 2019
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Suture retention strength of P(LLA-CL) tissue-engineered vascular grafts

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Abstract

The suture retention strength of artificial vascular grafts is a key mechanical property that affects the function of the grafts. Different from the conventional method of testing the suture retention strength, this study simulated the actual suturing state of vascular scaffolds approximately and investigated the effect of graft type, graft wall thickness, and number of stitches on the suture retention strength of poly(L-lactide-co-ε-caprolactone) P(LLA-CL) vascular grafts. The results showed that the P(LLA-CL) tissue-engineered vascular scaffolds have excellent suture performance and, when the graft wall thickness is greater than 0.24 mm, the suture retention strength will meet the vascular transplantation standard. Under the same conditions, the greater the number of stitches, the more uniform the force of the anastomosis and then the greater the suture retention strength. This experiment provides a more comprehensive and accurate suture retention strength value for the application of P(LLA-CL) tissue engineered vascular grafts, which helps to guide the further optimization of tissue-engineered vascular grafts to meet specific mechanical performance requirements.

Graphical abstract: Suture retention strength of P(LLA-CL) tissue-engineered vascular grafts

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Article information


Submitted
17 Jun 2019
Accepted
02 Jul 2019
First published
09 Jul 2019

This article is Open Access

RSC Adv., 2019,9, 21258-21264
Article type
Paper

Suture retention strength of P(LLA-CL) tissue-engineered vascular grafts

X. Meng, X. Wang, Y. Jiang, B. Zhang, K. Li and Q. Li, RSC Adv., 2019, 9, 21258
DOI: 10.1039/C9RA04529E

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

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    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
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    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
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    [Original citation] - Published by The Royal Society of Chemistry.

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