Issue 63, 2018, Issue in Progress

Electrochemiluminescence of gold nanoparticles and gold nanoparticle-labelled antibodies as co-reactants

Abstract

Gold nanoparticles (AuNPs) and AuNP-labelled antibodies can participate in the electrochemiluminescence (ECL) reaction of tris(2,2′-bipyridyl) ruthenium(II) (Ru(bpy)32+) as a co-reactant. The electrochemical and spectral characteristics of this new ECL system were confirmed by experiments, and its reaction mechanism was speculated to be different from that of typical ECL. The experimental results showed that the new ECL system exhibited higher ECL efficiency, and AuNP-labelled substances can be sensitively measured with the help of AuNPs. Based on the dual role of AuNPs as a co-reactant and marker, the AuNP–Ru(bpy)32+ ECL system will be a useful tool in biochemical analysis.

Graphical abstract: Electrochemiluminescence of gold nanoparticles and gold nanoparticle-labelled antibodies as co-reactants

Article information

Article type
Paper
Submitted
06 Sep 2018
Accepted
07 Oct 2018
First published
24 Oct 2018
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2018,8, 36219-36222

Electrochemiluminescence of gold nanoparticles and gold nanoparticle-labelled antibodies as co-reactants

C. Zhao, L. Niu, X. Wang and W. Sun, RSC Adv., 2018, 8, 36219 DOI: 10.1039/C8RA07429A

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