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Issue 57, 2018
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Reduced graphene oxide-supported methylene blue nanocomposite as a glucose oxidase-mimetic for electrochemical glucose sensing

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Abstract

In this paper, a hybrid nanocomposite (MB-rGO) was synthesized based on the π–π stacking interactions between methylene blue (MB) and reduced graphene oxide (rGO). The as-synthesized nanocomposite was characterized by SEM, TEM, XRD, FTIR, UV-vis and XPS spectra. UV-vis spectroscopy and electrochemical tests suggested the MB-rGO modified on the electrode exhibited glucose oxidase-mimetic catalytic activity towards glucose, and displayed excellent electrocatalytic performance for electrochemical detection of glucose with a wide linear range from 1.04 to 17.44 mM, a low detection limit of 45.8 μM and a large sensitivity of 13.08 μA mM−1 cm−2. The proposed glucose sensor also showed high stability, reproducibility and good abilities of anti-interference to dopamine, ascorbic acid and uric acid. Moreover, the modified electrode was used to determine glucose concentration in human blood serum samples with satisfactory results.

Graphical abstract: Reduced graphene oxide-supported methylene blue nanocomposite as a glucose oxidase-mimetic for electrochemical glucose sensing

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Supplementary files

Article information


Submitted
22 Jul 2018
Accepted
13 Sep 2018
First published
20 Sep 2018

This article is Open Access

RSC Adv., 2018,8, 32565-32573
Article type
Paper

Reduced graphene oxide-supported methylene blue nanocomposite as a glucose oxidase-mimetic for electrochemical glucose sensing

S. Yang, D. Liu, Q. B. Meng, S. Wu and X. Song, RSC Adv., 2018, 8, 32565
DOI: 10.1039/C8RA06208K

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