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Issue 22, 2018, Issue in Progress
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Microencapsulated sunblock nanoparticles based on zeolitic imidazole frameworks for safe and effective UV protection

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Abstract

Sunscreen is believed to protect human skin from photo damage due to UV exposure. However, substantial concerns remain associated with skin contact with UV filters and the subsequent reactive oxygen species from photoactivation of UV filters. Herein, we show that the microencapsulation of octyl p-methoxycinnamate (OMC), a typical UV filter, into the nanoporous structure of zeolitic imidazole frameworks (ZIF-8) prevents the skin exposure to UV filters while improving UV protection performance. Meanwhile, the UV filter photostability has been obviously improved due to the nanoconfinement effect. Microencapsulated OMC in ZIF-8 adhered to the stratum corneum could not only reduce OMC transdermal penetration, but also prevent skin exposure to the deleterious reactive oxygen species (ROS) from photoactivation of OMC. Therefore, this microencapsulated UV filter system based on a metal organic frameworks microporous polymer would find important applications in skin care products through providing safe and effective UV protection.

Graphical abstract: Microencapsulated sunblock nanoparticles based on zeolitic imidazole frameworks for safe and effective UV protection

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Article information


Submitted
22 Jan 2018
Accepted
19 Mar 2018
First published
29 Mar 2018

This article is Open Access

RSC Adv., 2018,8, 12315-12321
Article type
Paper

Microencapsulated sunblock nanoparticles based on zeolitic imidazole frameworks for safe and effective UV protection

L. Xu, D. Wu, B. Zhou, Y. Xu, W. Wang, D. Yu and D. Luo, RSC Adv., 2018, 8, 12315
DOI: 10.1039/C8RA00632F

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

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    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
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    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
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    [Original citation] - Published by The Royal Society of Chemistry.

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