Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery

Chuang Zhao; K. P. Rakesh; Saira Mumtaz; Balakrishna Moku; Abdullah M. Asiri; Hadi M. Marwani; H. M. Manukumar; Hua-Li Qin

doi:10.1039/C7RA13754K

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Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery

Chuang Zhao,^a K. P. Rakesh,

*^ab Saira Mumtaz,^a Balakrishna Moku,^a Abdullah M. Asiri,

^c Hadi M. Marwani,^c H. M. Manukumar

^d and Hua-Li Qin

*^a

Author affiliations

* Corresponding authors

^a Department of Pharmaceutical Engineering, School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, 205 Luoshi Road, Wuhan, PR China
E-mail: rakeshasg@gmail.com, qinhuali@whut.edu.cn
Fax: +86 13007173116

^b Sri Ram Chem, R & D Centre, Plot No. 31, JCK Industrial Park, Belagola Industrial Area, Mysore 570016, Karnataka, India

^c Department of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia

^d Department of Studies in Biotechnology, University of Mysore, Manasagangotri, Mysuru-570006, Karnataka, India

Abstract

Arylnaphthalene lactones are natural products extracted from a wide range of different parts of plants. The progressing interest in the synthesis of these compounds is due to their significant biological activities, which have made them potential candidates in drug discovery and development. This review mainly covers recent developments in the synthesis and biological applications of arylnaphthalene lactone analogs.

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DOI: https://doi.org/10.1039/C7RA13754K
Article type: Review Article
Submitted: 30 Dec 2017
Accepted: 26 Feb 2018
First published: 06 Mar 2018
This article is Open Access

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RSC Adv., 2018,8, 9487-9502

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Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery

C. Zhao, K. P. Rakesh, S. Mumtaz, B. Moku, Abdullah M. Asiri, H. M. Marwani, H. M. Manukumar and H. Qin, RSC Adv., 2018, 8, 9487 DOI: 10.1039/C7RA13754K

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Arylnaphthalene lactone analogues: synthesis and development as excellent biological candidates for future drug discovery

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