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Issue 68, 2017, Issue in Progress
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Facile and sensitive chemiluminescence detection of H2O2 and glucose by a gravity/capillary flow and cloth-based low-cost platform

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Abstract

This paper describes the development of a cloth-based CL strategy that can quantify H2O2 or glucose in a low-cost, easy-to-use, rapid and sensitive manner. Wax screen-printing is applied to fabricate the ultralow-cost cloth-based devices, and thus the as-prepared sensors have a very low cost (about $0.01 per assay). Moreover, an inexpensive CCD camera is used to image the light from the gravity/capillary flow-triggered enzyme-catalysed oxidation of luminol by H2O2. Under optimized conditions, the developed CL platform can fulfill the determination of H2O2, with a linear range of 0.01–10 mM and a detection limit of 9.07 μM. Similarly, glucose can be detected in the range of 0.01–10 mM, with a detection limit of 9.74 μM. Additionally, the RSDs of these two assays are 3.36%, 3.66% and 2.64% for 0.01, 0.1 and 5 mM H2O2, and 3.01%, 2.80% and 3.68% for 0.1, 1 and 5 mM glucose, respectively. Moreover, the devices can maintain ∼95% of their initial response for three weeks, and tolerate a series of interfering species at reasonable concentrations. Therefore, the proposed platform has an acceptable sensitivity, linear range, reproducibility and stability. Finally, this platform is successfully applied to the detection of H2O2 in milk and glucose in human serum.

Graphical abstract: Facile and sensitive chemiluminescence detection of H2O2 and glucose by a gravity/capillary flow and cloth-based low-cost platform

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Publication details

The article was received on 16 Jun 2017, accepted on 30 Aug 2017 and first published on 06 Sep 2017


Article type: Paper
DOI: 10.1039/C7RA06721F
Citation: RSC Adv., 2017,7, 43245-43254
  • Open access: Creative Commons BY-NC license
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    Facile and sensitive chemiluminescence detection of H2O2 and glucose by a gravity/capillary flow and cloth-based low-cost platform

    H. Li, D. Wang, C. Liu, R. Liu and C. Zhang, RSC Adv., 2017, 7, 43245
    DOI: 10.1039/C7RA06721F

    This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

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