Issue 58, 2017, Issue in Progress
From the journal:

RSC Advances

An electrochemical biosensor for detection of the sepsis-related biomarker procalcitonin†

Jong Min Lim,a   Myung Yi Ryu,a   Ji Hong Kim,a   Chae Hwan Cho,a   Tae Jung Parkb  and  Jong Pil Park ORCID logo *a  

* Corresponding authors

a Department of Pharmaceutical Engineering, Daegu Haany University, Gyeongsan 38610, Republic of Korea
E-mail: jppark@dhu.ac.kr
Fax: +82-53-819-1406

b Department of Chemistry, Chung-Ang University, Seoul 06974, Republic of Korea

Abstract

An electrochemical peptide sensor employing a sensitive synthetic peptide was designed for the diagnosis of sepsis. A series of synthetic peptides were chemically synthesized, and the binding events and performance of the sensor were monitored by CV and EIS. PCT BP3, selected as a potential high-affinity peptide, was found to have a Kd value of 0.39 ± 0.11 nM for procalcitonin.

Graphical abstract: An electrochemical biosensor for detection of the sepsis-related biomarker procalcitonin

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Article information

DOI
https://doi.org/10.1039/C7RA06553A
Article type
Paper
Submitted
12 Jun 2017
Accepted
18 Jul 2017
First published
21 Jul 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 36562-36565

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An electrochemical biosensor for detection of the sepsis-related biomarker procalcitonin

J. M. Lim, M. Y. Ryu, J. H. Kim, C. H. Cho, T. J. Park and J. P. Park, RSC Adv., 2017, 7, 36562 DOI: 10.1039/C7RA06553A

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