Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 25, 2017
Previous Article Next Article

A poly(amidoamine) dendrimer-based drug carrier for delivering DOX to gliomas cells

Author affiliations

Abstract

A drug delivery carrier G4–FA–PEG with PEG and FA modified on the periphery of G4.0 poly(amidoamine) (PAMAM) dendrimer was synthesized, and doxorubicin (DOX) was encapsulated in the interior. The in vitro cytotoxicity and cellular uptake in gliomas cells were both enhanced via a FR-mediated endocytosis pathway.

Graphical abstract: A poly(amidoamine) dendrimer-based drug carrier for delivering DOX to gliomas cells

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Jan 2017, accepted on 03 Mar 2017 and first published on 08 Mar 2017


Article type: Paper
DOI: 10.1039/C7RA00713B
Citation: RSC Adv., 2017,7, 15475-15481
  • Open access: Creative Commons BY-NC license
  •   Request permissions

    A poly(amidoamine) dendrimer-based drug carrier for delivering DOX to gliomas cells

    Y. Li, H. He, W. Lu and X. Jia, RSC Adv., 2017, 7, 15475
    DOI: 10.1039/C7RA00713B

    This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material and it is not used for commercial purposes.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements