New page to access pyridine derivatives: synthesis from N-propargylamines

Abstract

The pyridine is one of the simplest, yet most important N-heterocycles. This ring is utilized in more than 100 drugs and this number is increasing by the day. Therefore, synthesis of these compounds using new protocols is always interesting. This review surveys research work on the preparation of pyridines and their ring fused analogues from N-propargylamines. In this review, we have classified these reactions based on the type and the desired products.