Issue 45, 2016, Issue in Progress

New microsecond intramolecular reactions of human telomeric DNA in solution

Abstract

Careful T-jump relaxation kinetic experiments in the microsecond timescale conducted in dilute solutions of human telomeric DNA at pH = 7.5 and 25 °C, have evinced for the first time two different equilibria. The sets of data recorded concur with two G-quadruplex ↔ G-triplex equilibria coexisting in the presence of both Na+ and K+-buffer ions.

Graphical abstract: New microsecond intramolecular reactions of human telomeric DNA in solution

Article information

Article type
Communication
Submitted
16 Feb 2016
Accepted
07 Apr 2016
First published
08 Apr 2016

RSC Adv., 2016,6, 39204-39208

Author version available

New microsecond intramolecular reactions of human telomeric DNA in solution

C. Pérez-Arnáiz, N. Busto, J. M. Leal and B. García, RSC Adv., 2016, 6, 39204 DOI: 10.1039/C6RA04203A

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