Issue 22, 2016
From the journal:

RSC Advances

A novel carbazole-based mitochondria-targeted ratiometric fluorescent probe for bisulfite in living cells†

Gang Wang,*a   Hao Chen,b   Xiuli Chenb  and  Yongmei Xie*b  

* Corresponding authors

a Zunyi Medical College, Zunyi, Guizhou Province, China
E-mail: wg8855350@163.com

b State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan Province, P. R. China
E-mail: xieym@scu.edu.cn

Abstract

A novel mitochondria-targeted ratiometric fluorescent probe was developed via condensation of carbazole with two indolium units, which could realize the detection of bisulfite in a PBS buffer solution. The probe exhibited good mitochondrial location ability and could selectively respond to bisulfite among other sulfur-containing species in living cells.

Graphical abstract: A novel carbazole-based mitochondria-targeted ratiometric fluorescent probe for bisulfite in living cells

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Article information

DOI
https://doi.org/10.1039/C5RA27805H
Article type
Communication
Submitted
27 Dec 2015
Accepted
08 Feb 2016
First published
09 Feb 2016

RSC Adv., 2016,6, 18662-18666

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A novel carbazole-based mitochondria-targeted ratiometric fluorescent probe for bisulfite in living cells

G. Wang, H. Chen, X. Chen and Y. Xie, RSC Adv., 2016, 6, 18662 DOI: 10.1039/C5RA27805H

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