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Issue 29, 2016
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Catalyst-free microwave-assisted arylglyoxal-based multicomponent reactions for the synthesis of fused pyrans

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Abstract

A series of functionalized pyrans fused with quinolones, naphthoquinones, coumarins and pyrones have been synthesized using three component reactions of arylglyoxal monohydrate, malononitrile, and a wide range of cyclic 1,3-dicarbonyls under microwave irradiation. This method is a simple and straightforward method for the easy access of fused and functionalized pyrans tethered with an aroyl group without involving any catalyst and column chromatographic purifications.

Graphical abstract: Catalyst-free microwave-assisted arylglyoxal-based multicomponent reactions for the synthesis of fused pyrans

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Publication details

The article was received on 01 Dec 2015, accepted on 14 Feb 2016 and first published on 03 Mar 2016


Article type: Paper
DOI: 10.1039/C5RA25536H
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RSC Adv., 2016,6, 24464-24469

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    Catalyst-free microwave-assisted arylglyoxal-based multicomponent reactions for the synthesis of fused pyrans

    R. Mishra and L. H. Choudhury, RSC Adv., 2016, 6, 24464
    DOI: 10.1039/C5RA25536H

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