Issue 9, 2016
From the journal:

RSC Advances

Mild and ambient annulations for pyrrole synthesis from amines and arylacetaldehydes†

Huawen Huang,*a   Lichang Tang,a   Jinhui Caia  and  Guo-Jun Deng*a  

* Corresponding authors

a Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China
E-mail: hwhuang@xtu.edu.cn, gjdeng@xtu.edu.cn

Abstract

A mild and ambient pyrrole synthesis via copper-catalyzed aerobic cyclization of alkylamines and arylacetaldehydes is described. This method provided alternative access to a range of 1,3,4-trisubstituted pyrroles under environmentally friendly reaction conditions.

Graphical abstract: Mild and ambient annulations for pyrrole synthesis from amines and arylacetaldehydes

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Article information

DOI
https://doi.org/10.1039/C5RA24006A
Article type
Communication
Submitted
13 Nov 2015
Accepted
06 Jan 2016
First published
11 Jan 2016

RSC Adv., 2016,6, 7011-7014

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Mild and ambient annulations for pyrrole synthesis from amines and arylacetaldehydes

H. Huang, L. Tang, J. Cai and G. Deng, RSC Adv., 2016, 6, 7011 DOI: 10.1039/C5RA24006A

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