Issue 100, 2015
From the journal:

RSC Advances

Iodine-mediated regioselective C–N and C–I bond formation of alkenes†

Kai Sun,*ab   Fengji Ma,b   Lulu Liu,b   Jingjing Sun,b   Xin Liu,b   Yachao Wang,b   Zhiguo Zhang*a  and  Guisheng Zhang*a  

* Corresponding authors

a Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, P. R. China
E-mail: sunk468@nenu.edu.cn, zhangzg@htu.edu.cn, zgs6668@yahoo.com

b College of Chemistry and Chemical Engineering Anyang Normal University, Anyang, Henan 455000, P. R. China

Abstract

Iodine-mediated intermolecular C–N and C–I bond formation of alkenes is described. A series of alkenes could be selectively converted into the corresponding aminoiodination products, which are versatile building blocks in organic synthesis and medicinal chemistry. Wide substrate scope, broad functional group tolerance and easy scale-up operation make this protocol very practical and attractive in synthetic chemistry.

Graphical abstract: Iodine-mediated regioselective C–N and C–I bond formation of alkenes

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Article information

DOI
https://doi.org/10.1039/C5RA14407H
Article type
Communication
Submitted
21 Jul 2015
Accepted
24 Sep 2015
First published
24 Sep 2015

RSC Adv., 2015,5, 82492-82495

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Iodine-mediated regioselective C–N and C–I bond formation of alkenes

K. Sun, F. Ma, L. Liu, J. Sun, X. Liu, Y. Wang, Z. Zhang and G. Zhang, RSC Adv., 2015, 5, 82492 DOI: 10.1039/C5RA14407H

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