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Issue 86, 2015
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One-pot regioselective synthesis of functionalized and fused furans from Morita–Baylis–Hillman and Rauhut–Currier adducts of nitroalkenes

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Abstract

Highly functionalized and fused furans have been synthesized via cascade reactions of Morita–Baylis–Hillman and Rauhut–Currier adducts of nitroalkenes with active methylene compounds. The reactions involving SN2′-intramolecular Michael addition or Michael addition-intra-molecular nucleophilic substitution take place in a regioselective manner to afford synthetically and biologically useful furans in moderate to good yields.

Graphical abstract: One-pot regioselective synthesis of functionalized and fused furans from Morita–Baylis–Hillman and Rauhut–Currier adducts of nitroalkenes

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Article information


Submitted
16 Jun 2015
Accepted
10 Aug 2015
First published
10 Aug 2015

This article is Open Access

RSC Adv., 2015,5, 69990-69999
Article type
Paper
Author version available

One-pot regioselective synthesis of functionalized and fused furans from Morita–Baylis–Hillman and Rauhut–Currier adducts of nitroalkenes

V. Mane, T. Kumar, S. Pradhan, S. Katiyar and I. N. N. Namboothiri, RSC Adv., 2015, 5, 69990
DOI: 10.1039/C5RA11471C

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