Gold nanoparticle catalyzed intramolecular C–S bond formation/C–H bond functionalization/cyclization cascades

Abstract

An efficient synthesis of 2-(N-aryl)aminobenzo[d]-1,3-thiazoles via intramolecular C–S bond formation/C–H bond functionalization utilizing an unusual cocatalytic Au-NPs/KMnO₄ system under an oxygen atmosphere at 80 °C is presented. Au-NPs can be easily prepared by using HAuCl₄ with reductive potential of Kayea assamica (sia nahor) aqueous fruit extract. The catalyst can be easily separated and recycled eight times without any appreciable loss of activity.