Issue 74, 2015
From the journal:

RSC Advances

Doxorubicin loaded chitosan–ZnO hybrid nanospheres combining cell imaging and cancer therapy†

Huiyue Zhao,a   Pin Lv,a   Da Huo,a   Chao Zhang,a   Yin Ding,*b   Peipei Xuc  and  Yong Hu*a  

* Corresponding authors

a College of Engineering and Applied Sciences, Nanjing University, Nanjing 210093, China
E-mail: hvyong@nju.edu.cn

b State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China
E-mail: dingyin@nju.edu.cn

c Department of Radiology, Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu, P. R. China

Abstract

We report chitosan–ZnO nanoparticles (CZNPs), which have enhanced photoluminescence stability and longer retention time in cells compared with pure ZnO QDs. These CZNPs can illuminate the cells, show the distribution of the nanospheres in the cell, and thus monitor the fate of the loaded drug, which enable these CZNPs to have a promising future in cell imaging and cancer therapy.

Graphical abstract: Doxorubicin loaded chitosan–ZnO hybrid nanospheres combining cell imaging and cancer therapy

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Article information

DOI
https://doi.org/10.1039/C5RA09587E
Article type
Communication
Submitted
21 May 2015
Accepted
08 Jul 2015
First published
08 Jul 2015

RSC Adv., 2015,5, 60549-60551

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Doxorubicin loaded chitosan–ZnO hybrid nanospheres combining cell imaging and cancer therapy

H. Zhao, P. Lv, D. Huo, C. Zhang, Y. Ding, P. Xu and Y. Hu, RSC Adv., 2015, 5, 60549 DOI: 10.1039/C5RA09587E

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