Issue 60, 2015

Self-assembly, photoresponsive behavior and transport potential of azobenzene grafted dendronized polymeric amphiphiles

Abstract

Photoresponsive polymeric amphiphiles were developed by first synthesizing the polyester chain via Novozym 435 catalyzed step growth, condensation polymerization of poly[ethylene glycol bis(carboxymethyl) ether]diethylester and 2-azidopropan-1,3-diol followed by grafting with 4′-butyl-4-propargyloxy(azobenzene) and [G2.0] polyglycerol dendron by using a ‘Click chemistry’ approach. The resulting polymers were observed to form supramolecular micellar aggregates in aqueous solution. The critical aggregation concentration (CAC) was determined via fluorescence measurements and using ‘Nile red’ as a probe. The nano-structures formed in the aqueous solution were characterized by dynamic light scattering (DLS) and cryo-TEM measurements. The encapsulation potential of polymeric amphiphiles for Nile red and curcumin as well as their release via transcis photoisomerization of the embedded azobenzene moiety was studied, by absorbance and fluorescence spectroscopy techniques. The developed polymeric micellar systems behave as efficient photoresponsive smart nanocarriers.

Graphical abstract: Self-assembly, photoresponsive behavior and transport potential of azobenzene grafted dendronized polymeric amphiphiles

Supplementary files

Article information

Article type
Paper
Submitted
01 May 2015
Accepted
22 May 2015
First published
22 May 2015

RSC Adv., 2015,5, 48301-48310

Author version available

Self-assembly, photoresponsive behavior and transport potential of azobenzene grafted dendronized polymeric amphiphiles

M. Kumari, M. Billamboz, E. Leonard, C. Len, C. Böttcher, A. K. Prasad, R. Haag and S. K. Sharma, RSC Adv., 2015, 5, 48301 DOI: 10.1039/C5RA08047A

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