Issue 74, 2015

Highly efficient synthesis of amides from ketoximes using trifluoromethanesulphonic anhydride

Abstract

Trifluoromethanesulphonic anhydride (triflic anhydride: TA) has been successfully used as a reagent for Beckmann rearrangement in the conversion of a variety of ketoximes into amides without any additive or base. This reagent works well for the synthesis of a library of amides with excellent yields.

Graphical abstract: Highly efficient synthesis of amides from ketoximes using trifluoromethanesulphonic anhydride

Supplementary files

Article information

Article type
Paper
Submitted
28 Apr 2015
Accepted
03 Jul 2015
First published
07 Jul 2015

RSC Adv., 2015,5, 60106-60113

Author version available

Highly efficient synthesis of amides from ketoximes using trifluoromethanesulphonic anhydride

R. G. Kalkhambkar and H. M. Savanur, RSC Adv., 2015, 5, 60106 DOI: 10.1039/C5RA07789C

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