Issue 68, 2015
From the journal:

RSC Advances

A novel type of AIE material as a highly selective fluorescent sensor for the detection of cysteine and glutathione†

Xiaochen Tan,a   Yanan Du,a   Bingchuan Yang*a  and  Chen Ma*ab  

* Corresponding authors

a School of Chemistry and Chemical Engineering, Shandong University, Jinan, P. R. China

b State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China
E-mail: chenma@sdu.edu.cn

Abstract

A facile and efficient method was developed for the synthesis of isothiazolo[5,4-b]pyridin-3(2H)-one derivatives. This new type of AIE materials was studied through photophysical analysis, X-ray and theoretical calculations. Then, based on a ring-opening reaction, we found a useful application of this material in cysteine and glutathione detection.

Graphical abstract: A novel type of AIE material as a highly selective fluorescent sensor for the detection of cysteine and glutathione

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Article information

DOI
https://doi.org/10.1039/C5RA06244F
Article type
Paper
Submitted
08 Apr 2015
Accepted
17 Jun 2015
First published
17 Jun 2015

RSC Adv., 2015,5, 55165-55169

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A novel type of AIE material as a highly selective fluorescent sensor for the detection of cysteine and glutathione

X. Tan, Y. Du, B. Yang and C. Ma, RSC Adv., 2015, 5, 55165 DOI: 10.1039/C5RA06244F

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