Issue 31, 2015
From the journal:

RSC Advances

An efficient catalyst-free chemoselective multicomponent reaction for the synthesis of pyrimidine functionalized pyrrolo-annelated derivatives†

Yuvaraj Dommaraju,a   Somadrita Borthakur,a   Nimmakuri Rajesha  and  Dipak Prajapati*a  

* Corresponding authors

a Medicinal Chemistry Division, CSIR-North-East Institute of Science and Technology, Jorhat, Assam 785006, India
E-mail: dr_dprajapati2003@yahoo.co.uk
Fax: +91 376 2370011

Abstract

An efficient method for the synthesis of pyrimidine functionalized pyrrolo-annelated derivatives has been developed via a catalyst-free, one-pot chemoselective multicomponent domino reaction. The method offers ease of execution, easy and column free separation, mild reaction conditions, and high yields.

Graphical abstract: An efficient catalyst-free chemoselective multicomponent reaction for the synthesis of pyrimidine functionalized pyrrolo-annelated derivatives

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Article information

DOI
https://doi.org/10.1039/C5RA00796H
Article type
Paper
Submitted
14 Jan 2015
Accepted
25 Feb 2015
First published
25 Feb 2015

RSC Adv., 2015,5, 24327-24335

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An efficient catalyst-free chemoselective multicomponent reaction for the synthesis of pyrimidine functionalized pyrrolo-annelated derivatives

Y. Dommaraju, S. Borthakur, N. Rajesh and D. Prajapati, RSC Adv., 2015, 5, 24327 DOI: 10.1039/C5RA00796H

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