Issue 43, 2015

In situ growth of metallic silver on glucose oxidase for a highly sensitive glucose sensor

Abstract

This work presents a new idea to fabricate an enzyme glucose sensor. A bio-composite was assembled by in situ reducing Ag+ to Ag in glucose oxidase (GOD) solution. In this way, metallic silver can directly deposit onto the GOD surface and induce tight contact between Ag and GOD. The obtained composites were characterized by FESEM, EDS mapping, FTIR, CD, and electrochemical measurements. The Ag–GOD composite formed by an in situ reducing process exhibits facile, direct electrochemistry and good electrocatalytic performance without any electron mediator. The designed glucose biosensor shows high sensitivity, high selectivity, long life and accurate measurement in real serum samples, which is contributed to by a fast, direct electron transfer due to close proximity between Ag and GOD.

Graphical abstract: In situ growth of metallic silver on glucose oxidase for a highly sensitive glucose sensor

Article information

Article type
Paper
Submitted
05 Jan 2015
Accepted
09 Apr 2015
First published
09 Apr 2015

RSC Adv., 2015,5, 34486-34490

Author version available

In situ growth of metallic silver on glucose oxidase for a highly sensitive glucose sensor

Q. Sun, Y. Yu, J. Li and S. Bao, RSC Adv., 2015, 5, 34486 DOI: 10.1039/C5RA00134J

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