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Issue 20, 2015
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Formal [4 + 1] cycloaddition of o-quinone methides: facile synthesis of dihydrobenzofurans

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Abstract

An efficient and straightforward method for the rapid synthesis of 2-substituted dihydrobenzofurans has been developed via reaction of sulfur ylides with o-quinone methides (o-QMs), which were generated under mild conditions. The products could be obtained in excellent yields with various kinds of sulfur ylides.

Graphical abstract: Formal [4 + 1] cycloaddition of o-quinone methides: facile synthesis of dihydrobenzofurans

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Article information


Submitted
24 Dec 2014
Accepted
22 Jan 2015
First published
22 Jan 2015

RSC Adv., 2015,5, 14953-14957
Article type
Paper

Formal [4 + 1] cycloaddition of o-quinone methides: facile synthesis of dihydrobenzofurans

X. Lei, C. Jiang, X. Wen, Q. Xu and H. Sun, RSC Adv., 2015, 5, 14953
DOI: 10.1039/C4RA17003B

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