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Issue 29, 2015
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Controllable and mass fabrication of highly luminescent N-doped carbon dots for bioimaging applications

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Abstract

A facile but effective bottom-up method for the mass preparation of N-doped carbon dots (N–C-dots) was developed by the direct heating of a solid mixture of folic acid (FA) and sodium citrate (SC) for several minutes at 300 °C. The nitrogen content of the resulting N–C-dots could be easily and precisely tuned from 0% to 14% by adjusting the SC to FA mass ratio. Uniform N–C-dots with honeycomb-like ordered structures were obtained, with sizes ranging from 1 to 3 nm in diameter. The N-doping content affected not only the emission quantum yield but also the emission wavelength. The N–C-dots emitted strong blue-green fluorescence based on the excitation wavelength and N-doping content. Because of their excellent water solubility, low toxicity, powerful fluorescence, and high resistance to photobleaching, the N–C-dots can enter various cells and serve as ideal candidates for multicolour cell imaging.

Graphical abstract: Controllable and mass fabrication of highly luminescent N-doped carbon dots for bioimaging applications

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Publication details

The article was received on 24 Dec 2014, accepted on 12 Feb 2015 and first published on 13 Feb 2015


Article type: Paper
DOI: 10.1039/C4RA16990E
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RSC Adv., 2015,5, 22343-22349

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    Controllable and mass fabrication of highly luminescent N-doped carbon dots for bioimaging applications

    Z. Chen, X. Wang, H. Li, C. Li, Q. Lu, G. Yang, J. Long and L. Meng, RSC Adv., 2015, 5, 22343
    DOI: 10.1039/C4RA16990E

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