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Issue 27, 2015
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A simple yet effective fluorescent probe for detecting and imaging mercury ions in cells

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Abstract

We have synthesized rhodol hydrazide (RDH) as a simple fluorescent probe for detecting Hg2+. The probe can be applied in nontoxic solvents (EtOH and H2O). The probe has high selectivity and sensitivity to Hg2+ at pH 6–8. In addition, the probe has a superior capacity to resist interference from other ions. Both fluorescence intensity and absorbance have a linear relationship with the concentration of Hg2+, which ensured the precise detection of Hg2+. Furthermore, we have studied the intracellular Hg2+ imaging behavior of the probe on mammalian cells, which indicated that the probe can be applied to monitor Hg2+ within biological samples, especially in mammalian cells.

Graphical abstract: A simple yet effective fluorescent probe for detecting and imaging mercury ions in cells

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Publication details

The article was received on 12 Dec 2014, accepted on 06 Feb 2015 and first published on 06 Feb 2015


Article type: Paper
DOI: 10.1039/C4RA16267F
Citation: RSC Adv., 2015,5, 20634-20638

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    A simple yet effective fluorescent probe for detecting and imaging mercury ions in cells

    Y. Zhang, Q. Wang, P. Su, F. Zhao, J. Huang and B. Zhao, RSC Adv., 2015, 5, 20634
    DOI: 10.1039/C4RA16267F

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