Nickel oxide nanoparticles: a green and recyclable catalytic system for the synthesis of diindolyloxindole derivatives in aqueous medium

Abstract

This study focuses on the use of nano-NiO particles as green and inexpensive nanocatalysts for the synthesis of diindolyl oxindoles, an important class of potentially bioactive compounds. The oxindole derivatives were prepared by the condensation of indole and isatin compounds in water, an excellent solvent in terms of environmental impact and reduction of waste production.