Issue 3, 2015
From the journal:

RSC Advances

Acid- and metal-free synthesis of annulated pyrroles in a deep eutectic solvent†

Sunil M. Rokade,‡a   Ashok M. Garande,‡a   Nazim A. A. Ahmad‡a  and  Prakash M. Bhate*a  

* Corresponding authors

a Department of Dyestuff Technology, Institute of Chemical Technology (formerly UDCT), N. P. Marg, Matunga, Mumbai-400 019, Maharashtra, India
E-mail: pm.bhate@ictmumbai.edu.in, pmbhate@gmail.com
Tel: +91-22-3361-1111

Abstract

An environmentally benign, one-pot, three component synthesis of annulated pyrroles by coupling free sugars with enamines, generated in situ from aryl amines and 1,3-diketones, has been achieved by using a deep eutectic solvent (DES). The reaction conditions are mild and do not require additional Bronsted or Lewis acid catalysts.

Graphical abstract: Acid- and metal-free synthesis of annulated pyrroles in a deep eutectic solvent

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Article information

DOI
https://doi.org/10.1039/C4RA14379E
Article type
Communication
Submitted
12 Nov 2014
Accepted
28 Nov 2014
First published
01 Dec 2014

RSC Adv., 2015,5, 2281-2284

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Acid- and metal-free synthesis of annulated pyrroles in a deep eutectic solvent

S. M. Rokade, A. M. Garande, N. A. A. Ahmad and P. M. Bhate, RSC Adv., 2015, 5, 2281 DOI: 10.1039/C4RA14379E

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