Issue 16, 2015
From the journal:

RSC Advances

Domino reaction of N-(cyanomethyl)-1,3-azolium quaternary salts with o-hydroxybenzaldehydes: scope and limitations†

L. G. Voskressensky,*a   A. A. Festa,a   O. A. Storozhenko,a   T. A. Le,b   V. T. Nguyenc  and  A. V. Varlamova  

* Corresponding authors

a Organic Chemistry Department, Peoples' Friendship University of Russia, Miklukho-Maklaya st., 6., Moscow, Russian Federation
E-mail: lvoskressensky@sci.pfu.edu.ru

b Department of Chemistry, Vietnam National University, 144 Xuan Thuy, Cau Giay, Hanoi, Vietnam

c Institute of Chemistry, Vietnam Academy of Science & Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam

Abstract

A route towards chromenes, annulated with an imidazo[5,1-c][1,4]thiazine core through a base-promoted domino reaction of thiazolium quaternary salts, has been developed. The synthesised compounds show high cytotoxic activity against human tumour cell lines.

Graphical abstract: Domino reaction of N-(cyanomethyl)-1,3-azolium quaternary salts with o-hydroxybenzaldehydes: scope and limitations

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Article information

DOI
https://doi.org/10.1039/C4RA14122A
Article type
Paper
Submitted
08 Nov 2014
Accepted
13 Jan 2015
First published
14 Jan 2015

RSC Adv., 2015,5, 12442-12445

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Domino reaction of N-(cyanomethyl)-1,3-azolium quaternary salts with o-hydroxybenzaldehydes: scope and limitations

L. G. Voskressensky, A. A. Festa, O. A. Storozhenko, T. A. Le, V. T. Nguyen and A. V. Varlamov, RSC Adv., 2015, 5, 12442 DOI: 10.1039/C4RA14122A

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