Issue 105, 2014

Mildly basic ionic liquid catalyzed pseudo four component synthesis of 7,10-diaryl-7H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-amine derivatives under solvent-free conditions

Abstract

2-Hydroxyethylammonium formate [2-HEAF] as a mildly basic ionic liquid catalyzed the one-pot pseudo four component condensation reaction of aromatic aldehydes, α-naphthol, malononitrile, and ammonium acetate under thermal solvent-free conditions. This convenient and efficient procedure synthesized 7,10-diaryl-7H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-amine derivatives in short reaction times and good yields.

Graphical abstract: Mildly basic ionic liquid catalyzed pseudo four component synthesis of 7,10-diaryl-7H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-amine derivatives under solvent-free conditions

Article information

Article type
Paper
Submitted
26 Sep 2014
Accepted
05 Nov 2014
First published
06 Nov 2014

RSC Adv., 2014,4, 60543-60547

Mildly basic ionic liquid catalyzed pseudo four component synthesis of 7,10-diaryl-7H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-amine derivatives under solvent-free conditions

Hamid Reza Shaterian and Soheila Noura, RSC Adv., 2014, 4, 60543 DOI: 10.1039/C4RA11141A

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