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Issue 88, 2014
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BF3·OEt2-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C–C bond formation

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Abstract

A simple and efficient one pot protocol was developed for the synthesis of new structurally diverse 10-indolyldibenzo[b,f]azepine derivatives. The reaction involves Lewis-acid mediated ring expansion followed by C–C bond formation through nucleophilic addition of indole moiety.

Graphical abstract: BF3·OEt2-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C–C bond formation

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Publication details

The article was received on 15 Aug 2014, accepted on 22 Sep 2014 and first published on 23 Sep 2014


Article type: Paper
DOI: 10.1039/C4RA08723B
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RSC Adv., 2014,4, 47833-47840

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    BF3·OEt2-mediated one pot synthesis of 10-indolyldibenzo[b,f]azepine derivatives via tandem ring expansion and C–C bond formation

    T. Kotipalli, D. Janreddy, V. Kavala, C. Kuo, T. Kuo, M. Chen, C. He and C. Yao, RSC Adv., 2014, 4, 47833
    DOI: 10.1039/C4RA08723B

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